Journal of Food, Agriculture and Environment

In vitro anti adipogenic activity of Capsicum annuum (California wonder variety)

Author(s):

Manish R. Bhise, Ashish Kandalkar , Subhasri Mohapatra, Sanjay Vasu , Sunny Pahuja, Nitin S. Bhajipale

Recieved Date: 2022-11-02, Accepted Date: 2022-12-27

Abstract:

The plant Capsicum annuum Linn was collected and extraction of whole plant and fruit was carried out by soxhlation with methanol and water. All the extracts were screened for their cytotoxicity and antiadipogenic activity in vitro in 3T3-L1 cell line. The CTC₅₀ value was in the range of 103 to 250 μg/ml. Based on the cytotoxicity study the particular concentration were selected for antiadipogenic activity. The fat formation was estimated by oil red o staining. The methanolic extract of fruit showed good antiadipogenic activity at 100 μg/ml.

Keywords:

Capsicum annuum, methanol and water extracts, cytotoxicity, antiadipogenic activity, obesity

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Journal: Journal of Food, Agriculture and Environment
Year: 2023
Volume: 21
Issue: 1
Category: Food and Health
Pages: 14-16

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