Journal of Food, Agriculture and Environment
Vol 9,
Issue 3&4,2011
Online ISSN: 1459-0263
Print ISSN: 1459-0255
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Effect of dietary L-arginine and L-glutamine supplementation on H. parasuis infection
Author(s):
Guan Yang1,
Jinping Deng1, 2*, Wenkai Ren3, Gang Liu3, Run Cheng Li3, Xiaosong Wu1*, Dingding Su1Recieved Date: 2011-07-03, Accepted Date: 2011-09-29
Abstract:Haemophilus parasuis was the aetiological agent of Glässer’s disease characterized by fibrinous arthritis, polyserositis and meningitis. Glässer’s disease has become one of the most important respiratory diseases of pigs since first reported in 1910 by Glässer. Many disadvantages, such as emergence of other diseases, use of veterinary medicines, change of temperature and farm environment, may facilitate H. parasuis to live and propagate in vivo. Thus, big economic loss was caused by H. parasuis recently. Serum tumor necrosis factor alpha (TNF-α) level in the arginine group was significantly higher (P = 0.015) than the alanine group 48 hours after injection, but there is no difference in superoxide dismutase (SOD) activity in any treatments. Seventy-two hours after H. parasuis challenge, respectively, the the clinical protection rate of malondialdehyde (MDA), Creactive protein (CRP) and interleukin-1 beta (IL-1 beta) levels were found.
Keywords:Haemophilus parasuis,
L-arginine, L-glutamine, mouse modelJournal: Journal of Food, Agriculture and Environment
Year: 2011
Volume: 9
Issue: 3&4
Category: Agriculture
Pages: 588-591
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