Journal of Food, Agriculture and Environment




Vol 11, Issue 3&4,2013
Online ISSN: 1459-0263
Print ISSN: 1459-0255


Recovery and purification of sucralose-6-ester from the crystalline residue by macroporous resin


Author(s):

Bin Shen 1*, Bo Tang 1, Zhengqing Lu 2, Minghua Li 1, 2, 3, Jinshan Wu 3, Guoting Zhu 3

Recieved Date: 2013-05-22, Accepted Date: 2013-10-26

Abstract:

The sucralose-6-ester is the key intermediate in the synthesis of sucralose. The manufacture residue containing sucralose-6-ester was dissolved in water to prepare sample solution. Static adsorption and desorption studies were performed on three kinds of macroporous resins, and D101 resin was chosen for further experiment. The equilibrium data on D101 were well described by Langmuir and Freundlich models. Dynamic adsorption and desorption experiments were also performed using a packed column of D101 to optimize the separation process of sucralose-6-ester from aqueous solution. The optimum parameters for adsorption were an inlet sucralose-6-ester concentration of 18.4 mg/ml, a flow rate of 2 bed volume/h and the adsorption capacity is 29.4 mg(sucralose-6-ester)/ml(resin); for desorption, the elution process is performed by gradient solutions. After treatment of these conditions, the purity of sucralose-6-ester was increased to 41.8% with a recovery of 56.3% in the first separation, and to 64.7% with a recovery of 58.2% in the second separation, which reached the purity of sucralose-6-ester in the mixture of the chlorination reaction. In addition, the D101 resin column can be used for at least 5 times without reducing its adsorption property.

Keywords:

Sucralose, macroporous resin, adsorption, desorption, separation


Journal: Journal of Food, Agriculture and Environment
Year: 2013
Volume: 11
Issue: 3&4
Category: Food and Health
Pages: 63-66


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