Journal of Food, Agriculture and Environment

Concentration and mRNA abundance of growth hormone and insulin-like growth factor-I in serum, liver and longissimus dorsi of suckled Tibet and crossbred piglets during the early postnatal development

Author(s):

T. J. Li, Q. Hu, Z. Q. Liu, K. Yao, X. Wu, J. Pan, Y. L. Yin *

Recieved Date: 2010-07-27, Accepted Date: 2010-11-15

Abstract:

Early postnatal development change of growth hormone (GH) and insulin-like growth factor-I (IGF-I) of the two breeds including suckled Tibet piglets (on 1, 4, 7, 14, 21, 28, and 35 d after birth) and suckled crossbred piglets (Duroc×Landrace×Yorkshine) (on 1, 7, 14, 21 and 28 d after birth) were investigated in this study. There were significant differences (P<0.05) among ages during the early postnatal development for the concentration and mRNA abundance of growth hormone (GH) and insulin-like growth factor-I (IGF-I) and their receptors (R) in serum, liver and longissimus dorsi (LD) of the experimental piglets. There were the different dvelopment curve pattern (linear, quadratic, cubic or quartic) of age effects (P<0.05) on the concentration and mRNA expression of suckled crossbred piglets GH and IGF-I during the early postnatal development from 1 to 28 day of ages. Pearson's analysis showed serum GH concentration was correlated with serum IGF-I concentration, IGF-I mRNA abundance of LD, BW, and the relative body weight of LD. Serum IGF-I concentration correlated with liver IGF-I concentration, IGF-I mRNA abundance of LD, and BW. Liver IGF-I concentration correlated with GHR mRNA abundance of LD, IGF-I mRNA abundance of liver and LD, IGF-IR mRNA abundance of LD, BW, and the relative body weight of LD. LD IGF-I concentration correlated with IGF-I mRNA abundance of liver and LD, IGF-IR mRNA abundance of LD, and BW. Liver IGF-I mRNA abundance was correlated with GHR mRNA abundance of liver, IGF-I mRNA abundance of LD, BW and the relative body weight of LD. LD IGF-I mRNA abundance was correlated with GHR mRNA abundance of liver, IGF-IR mRNA abundance of LD, BW and the relative body weight of LD, respectively. Tibet suckled piglets had a lower (P<0.05) BW, concentration and mRNA abundance of GH, GHR, IGF-I and IGF-IR, except for GHR in LD and IGF-IR in liver, than those of the crossbred suckled piglets. There were the same development curve pattern of age effects (P<0.05) on serum IGF-I concentration (a linear pattern) and liver IGF-IR mRNA abundance (a cubic pattern) between suckled Tibet piglets on 1-35d after birth and suckled crossbred piglets on 1-28 d after birth during the early postnatal development. There were the same effect on the correlation for the two breeds among the concentration, mRNA abundance, BW and the relative body weight of LD, respectively.

Keywords:

Postnatal, Tibet piglets, crossbred piglets, liver, longissimus dorsi, GHR, IGF-I, IGF-IR

---

Journal: Journal of Food, Agriculture and Environment
Year: 2010
Volume: 8
Issue: 3&4
Category: Food and Health
Pages: 32-38

---

Full text for Subscribers

---

Information:

Note to users

The requested document is freely available only to subscribers/registered users with an online subscription to the Journal of Food, Agriculture & Environment. If you have set up a personal subscription to this title please enter your user name and password. All abstracts are available for free.

Article purchasing

If you like to purchase this specific document such as article, review or this journal issue, contact us. Specify the title of the article or review, issue, number, volume and date of the publication. Software and compilation, Science & Technology, all rights reserved. Your use of this website details or service is governed by terms of use. Authors are invited to check from time to time news or information.

---

Purchase this Article:   20 Purchase PDF Order Reprints for 15

---

Share this article :